Insect Neuromuscular Synapses
نویسندگان
چکیده
منابع مشابه
Neuromuscular facilitation and asthenic synapses.
Facilitation in neuromuscular junction of frog, i. e. successive enhancement of muscle action potential by repetitive stimulation, has been considered to be due to the recruitment of numbers of muscle fibres excited through junctions. It has been generally accepted that no neuromuscular facilitation is observed in the mammalian junctions (BROWN and HARVEY, 1941), except in curarized or fatigued...
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The formation of synapses requires a series of steps including the generation of neurons and their target cells, the guidance of axons to their targets, and the induction of a specialized presynaptic terminal and postsynaptic membrane. This review is primarily concerned with the inductive events that lead to postsynaptic differentiation. Because this phase of synapse formation begins only after...
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Although the effects of neurotrophins on survival and differentiation of various neuronal populations have been well studied, little is known about their role in synaptic development and function. We have investigated the long-term effects of neurotrophins in the maturation of neuromuscular synapses in Xenopus nerve-muscle cocultures. BDNF and NT-3, but not NGF, elicited significant changes in ...
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The neuromuscular synapse is a relatively large synapse with hundreds of active zones in presynaptic motor nerve terminals and more than ten million acetylcholine receptors (AChRs) in the postsynaptic membrane. The enrichment of proteins in presynaptic and postsynaptic membranes ensures a rapid, robust, and reliable synaptic transmission. Over fifty years ago, classic studies of the neuromuscul...
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Synaptic plasticity can last from a fraction of a second to weeks depending on how it was induced. The mechanisms that underlie short-, intermediate-, and long-term plasticity have been intensively studied at central synapses of both vertebrates and invertebrates; however, peripheral plasticity has not received as much attention. In this study, we investigated the mechanisms that contribute to ...
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ژورنال
عنوان ژورنال: American Zoologist
سال: 1973
ISSN: 0003-1569
DOI: 10.1093/icb/13.2.315